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KMID : 0903519860290020198
Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1986 Volume.29 No. 2 p.198 ~ p.206
Pattern of Molecular Aggregation of Ginsenosides in Aqueous Solution



Abstract
For the information on micellization at each ginsenoside level aqueous solution of purified saponin of Panax ginseng root was dialyzed through dialysis tubing (MW 12,000) or eluted through Bio-Gel P-2 (MW 200-2,000) and analysed for ginsenosides by high performance liquid chromatography. Ginsenosides can be classified into three groups depending upon molecular aggregation pattern and spatial arrangement of hydrophilic parts in molecule. Group ¥° that is large micelle former(aggregation number: above 10) and one side hydrophilic part (HP) includes ginsenosides Rb©û, Rb©ü, Rc and Rd (diols). Group ¥± thai is small micelle former (aggregation number:$gt; 10-1) and semi-two sales HP includes Rg©ü, Rf (triol) and Rg©ý (diol). Group ¥² that is no micelle former (aggregation number: 1) and two sides HP includes Re and Rg©û (triol).
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